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Ruy Pérez-Montfort Selected Research

Triose-Phosphate Isomerase (Triosephosphate Isomerase)

1/2016Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity.
4/2014New chemotypes as Trypanosoma cruzi triosephosphate isomerase inhibitors: a deeper insight into the mechanism of inhibition.
10/20131,2,4-thiadiazol-5(4H)-ones: a new class of selective inhibitors of Trypanosoma cruzi triosephosphate isomerase. Study of the mechanism of inhibition.
7/2002Highly specific inactivation of triosephosphate isomerase from Trypanosoma cruzi.

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Ruy Pérez-Montfort Research Topics

Disease

6Chagas Disease (American Trypanosomiasis)
01/2016 - 07/2002

Drug/Important Bio-Agent (IBA)

4Triose-Phosphate Isomerase (Triosephosphate Isomerase)IBA
01/2016 - 07/2002
3EnzymesIBA
01/2016 - 10/2013
1Pharmaceutical PreparationsIBA
01/2016
1NifurtimoxIBA
08/2015
1benzonidazole (benznidazole)IBA
08/2015
1ThiazolesIBA
07/2015